研究方向： 纳米药物/基因输送体系的构建及其癌症靶向治疗效果的评价。 多功能纳米复合物用于癌症免疫治疗的研究。 有机/无机纳米复合材料用于聚合酶链式反应的优化及其相关机制的研究。 联系电话：021-67792750 EMAIL：caoxy_116@dhu.edu.cn

个人简介：

曹雪雁，1982年1月生。2009年获得上海交通大学生物医学工程专业博士学位，现为东华大学生物工程系副研究员，中国生物材料委员会会员，上海市生物物理学会会员。目前承担《生物化学》和《细胞生物学实验》的本科教学工作，和《细胞生物学技术》的研究生教学工作。主持和参与了多项国家自然科学基金项目、上海市科委项目。近5年来在Angew. Chem.Int.，J. Am. Chem. Soc.， Nanoscale，Small，Biomaterials，Journal of Physical Chemistry C等国际知名学术杂志上发表五十余篇SCI论文。

近几年发表论著：

1. Hao Xinxin, Xu Bei, Chen Huan, Wang Xiaomeng, Zhang Jiulong, Guo Rui, *Shi Xiangyang, *Cao Xueyan. Stem cell-mediated delivery of nanogels loaded with ultrasmall iron oxide nanoparticles for enhanced tumor MR imaging, Nanoscale. 2019, 11, 4904-4910

2. Li Aijun, Qiu Jieru, Zhou Benqing, Xu Bei, Xiong Zhijuan, Hao Xinxin, *Shi Xiangyang, *Cao Xueyan. The gene transfection and endocytic uptake pathways mediated by PEGylated PEI-entrapped gold nanoparticles, Arabian Journal of Chemistry. DOI: 10.1016/j.arabjc.2018. 06.009, 2018, 0

3. Xu Be, Li Aijun, Hao Xinxin, Guo Rui, *Shi Xiangyan, *Cao Xueyan. PEGylated dendrimer-entrapped gold nanoparticles with low immunogenicity for targeted gene delivery , RSC Advances, 2018, 8(3): 1265~1273

4. Cao Xueyan, Lu Xueguang, Wang Dali, Jia Fei, Tan Xuyu, Corley Michelle, Chen Xiaoying, *Zhang Ke. Modulating the Cellular Immune Response of Oligonucleotides by Brush Polymer-Assisted Compaction , Small, 2017, 13(43): 1701432

5. Li Aijun, Zhou Benqing, Alves Carla S, Xu Bei, Guo Rui, *Shi Xiangyang, *Cao Xueyan. Mechanistic Studies of Enhanced PCR Using PEGylated PEI-Entrapped Gold Nanoparticles, ACS Applied Materials & Interfaces, 2016, 8(39): 25808~25817

6. Qiu Jieru, Kong Lingdan, Li Aijun, Wei Ping, Wang Lu, Cao Xueyan, Mignani Serge, Caminade Anne Marie, Majoral Jean Pierre, *Shi Xiangyang. Enhanced Delivery of Therapeutic siRNA into Glioblastoma Cells Using Dendrimer-Entrapped Gold Nanoparticles Conjugated with beta-Cyclodextrin, Nanomaterials, 2018, 8(3): 0~131

7. Yang Wenchao, Cao Xueyan, *Li Xinhui. Enhanced simultaneous overlap extension-PCR by gold nanoparticles, Nanomedicine: Nanotechnology, Biology and Medicine, 2017.10, 13(7): 2263~2266

8. Fei Jia, Xueguang Lu, Dali Wang, Xueyan Cao, Xuyu Tan, Hao Lu, *Ke Zhang. Depth-Profiling the Nuclease Stability and the Gene Silencing Efficacy of Brush-Architectured Poly(ethylene glycol)–DNA Conjugates , Journal of the American Chemical Society, 2017.8.9, 139(31): 10605~10608

9. Jia Fei, Lu Xueguang, Tan Xuyu, Wang Dali, Cao Xueyan, *Zhang Ke. Effect of PEG Architecture on the Hybridization Thermodynamics and Protein Accessibility of PEGylated Oligonucleotides, Angewandte Chemie International Edition, 2017, 56: 1239~1243

10. Zhang Haixia, Peng Chen, Li Aijun, *Shi Xiangyang, *Cao Xueyan. Effect of antifouling dendrimers and Au DENPs on the enhancement of PCR amplification , Canadian Journal of Chemistry, 2017, 95(9): 942~947