Dr. Rui Guo Department of Bioengineering, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University 2999 North Renmin Road, Shanghai, 201620,China Tel: +86-21-67792750 Fax : +86-21-67792306-804 E-mail: ruiguo@dhu.edu.cn

Education

09/2005– 06/2008：PhD study in polymer chemistry and physicsNanjing University, China

09/2002.– 06/2005：Masterstudy in polymer chemistry and physicsNanjing University, China

09/1998 – 06/2002：Bachelor study inapplied chemistryChina University of Petroleum, China

Professional experience

10/2010 – Now： Associated professor, Donghua University, China

06/2008 – 09/2010： Lecturer, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, China

Selected Publications since 2011

1. Zhuang,Y.; Zhao,L.; Zhen,L.; Hu,Y.; Ding, L.; Li, X.; Liu, C.; Zhao, J.; Shi, X.*; Guo,R.* A LAPONITE-polyethylenimine based theranostic nanoplatform for tumor-targeting CT imaging and chemotherapy. ACS Biomater. Sci. Eng.2017, 3, 431-442.

2. Ding, L.; Hu, Y.; Luo, Y. Ding, L.; Hu, Y.; Luo, Y.; Zhu, J. Z.; Wu, Y. L.; Yu, Z. B.; Cao, X. Y.; Peng, C.; Shi, X. Y.; Guo, R.* LAPONITE-stabilized iron oxide nanoparticles for in vivo MR imaging of tumors, Biomaterials Science, 2016, 4, 474-482.

3. Hou, W.; Wen, S.; Guo, R.*; Wang, S.; Shi, X.* Partially Acetylated Dendrimer-Entrapped Gold Nanoparticles with Reduced Cytotoxicity for Gene Delivery Applications, Journal of Nanoscience and Nanotechnology, 2015, 15, 4094-4105.

4. Chen, G.; Li, D.; Li, J.; Cao, X.; Wang, J.; Shi, X.; Guo, R.* Targeted doxorubicin delivery to hepatocarcinoma cells by lactobionic acid-modified laponite nanodisks, New Journal of Chemistry, 2015, 39, 2847-2855.

5. Mustafa, R.; Luo, Y.; Wu, Y.; Guo, R.*; Shi, X.* Dendrimer-Functionalized Laponite Nanodisks as a Platform for Anticancer Drug Delivery, Nanomaterials, 2015, 5, 1716-1731.

6. Zhang, M.; Guo, R.; Keri, M.; Banyai, I.*; Zheng, Y.; Cao, M.; Cao, X.; Shi, X.* Impact of Dendrimer Surface Functional Groups on the Release of Doxorubicin from Dendrimer Carriers. Journal of Physical Chemistry B 2014, 118: 1696-1706.

7. Qi, R.; Guo, R.*; Zheng, F.; Liu, H.; Yu, J.; Shi, X.* Controlled release and antibacterial activity of antibiotic loaded electrospun halloysite/poly(lactic-co-glycolic acid) composite nanofibers, Colloids and Surfaces B: Biointerfaces, 2013, 110, 148-155.

8. Wu, Y.; Guo, R.; Wen, S.; Shen, M.; Zhu, M.; Wang, J.; Shi, X.*, Folic acid-modified laponite nanodisks for targeted anticancer drug delivery. Journal of Materials Chemistry B, 2014, 2, 7410–7418.

9. Hou, W.; Wei, P.; Kong, L.; Guo, R.; Wang, S.; Shi, X.* Partially PEGylated dendrimer-entrapped gold nanoparticles: a promising nanoplatform for highly efficient DNA and siRNA delivery, Journal of Materials Chemistry B, 2016, 4, 2933-2943.

10. Liu, H.; Wang, H.; Xu,Y.; Guo, R.; Wen, S.;i Huang, Y.; Liu, W.; Shen, M.;* Zhao, J.; Zhang, G.; * Shi, X. * Lactobionic Acid-Modified Dendrimer-Entrapped Gold Nanoparticles for Targeted Computed Tomography Imaging of Human Hepatocellular Carcinoma, ACS Applied Material Interfaces 2014, 6, 6944-6953.

11. Wang, S.; Wu, Y.; Guo, R.; Huang, Y.; Wen, S.; Shen, M.; Wang, J.; Shi, X.*, Laponite Nanodisks as an Efficient Platform for Doxorubicin Delivery to Cancer Cells. Langmuir 2013, 29, 5030-5036.

12. Guo, R.; Yao, Y.; Cheng, G.; Wang, S. H.; Li, Y.; Shen, M.; Zhang, Y.; Baker, J. R.; Wang, J.; Shi, X.*, Synthesis of glycoconjugated poly(amindoamine) dendrimers for targeting human liver cancer cells. RSC Advances 2012, 2, 99-102.

13. Guo, R.; Shi, X.*, Dendrimers in Cancer Therapeutics and Diagnosis. Current Drug Metabolism 2012, 13, 1097-1109.

14. Guo, R.; Wang, H.; Peng, C.; Shen, M.; Zheng, L.; Zhang, G.; Shi, X.*, Enhanced X-ray attenuation property of dendrimer-entrapped gold nanoparticles complexed with diatrizoic acid. Journal of Materials Chemistry 2011, 21, 5120-5127.

15. Guo, R.; Cheng, Y.; Ding, D.; Li, X.; Zhang, L.; Jiang, X.*; Liu, B., Synthesis and Antitumoral Activity of Gelatin/Polyoxometalate Hybrid Nanoparticles. Macromolecular Bioscience 2011, 11, 839-847.