个人简历
文玫 博士
出生日期：1995年9月
籍 贯：四川省广元市
手机号码：18021078612
电子邮箱：2180276@mail.dhu.edu.cn
教育和工作经历
2023.06-至今：博士后，东华大学材料学院(陈志钢 教授)
2018.09-2023.06：硕博连读，东华大学材料学院(陈志钢 教授)
2014.09-2018.06：学士，东华大学，新能源与光电材料
研究领域
响应型仿生纤维的设计与开发
光/超声响应纳米试剂的制备、仿生伪装和肿瘤/心血管疾病多模式诊疗的研究
主持和参与项目
[1] 国家资助博士后研究人员计划C档，低剂量X射线驱动的仿生纳米胶囊的构筑及协同免疫治疗的研究(GZC20230419)，2023.06-2025.05，24
；
[2] 中国博士后75批面上项目，糖尿病伤口微环境响应型的Janus多功能纤维膜的构建及其治疗机制研究(2024M750402)，2024.07-2025.06，8
；
[3] 2020-2021年度中央高校基本科研业务费专项资金、东华大学研究生创新基金 (CUSF-DH-D-2021010)，2.4 万元，已结题；
[4] 上海市抗癌协会“雏鹰”计划，低剂量X射线驱动的仿生 MOF协同肿瘤免疫治疗的机制及应用的研究(SACA-CY23C05), 2024.01-2025.12, 1
；
主要研究论文 (#代表共同第一作者，*代表通讯作者)
以第一/通讯/共一作者身份在Advanced Functional Materials、Biomaterials、Nano Today、Bioactive Materials、Advanced Healthcare Materials等期刊发表论文13篇。
通讯作者4篇：
[1] Xiaojing Zhang#, Nuo Yu#, Qian Ren, Shining Niu, Liqiong Zhu, Ling Hong, Kangle Cui, Xiao Wang, Weizhong Jiang, Mei Wen*, Zhigang Chen*. Janus nanofiber membranes with photothermal-enhanced biofluid drainage and sterilization for diabetic wounds. Advanced Functional Materials, 2024, 34, 2315020.
[2] Liqiong Zhu, Weishuai Lian, Nuo Yu, Jialan Meng, Hongchun Zeng, Yue Wang, Xiao Wang, Mei Wen*, Zhigang Chen*. Erythrocyte-membrane-camouflaged magnetic nanocapsules with photothermal/magnetothermal effects for thrombolysis. Advanced Healthcare Materials, 2024, 2400127.
[3] Lin Hong, Pu Qiu, Shining Niu, Qian Chen, Fengkun Chen*, Mei Wen*, Nuo Yu*, Zhigang Chen. On site electrospinning nanofiber membranes incorporating V shaped organic semiconductors for multifunctional diabetic wound dressing. Advanced Fiber Materials, 2024, 6, 1413.
[4] Xiao Wang, Xiaojing Zhang, Wenjing Zhao, Liqiong Zhu, Lin Hong, Kangle Cui, Nuo Yu, Zhigang Chen*, Mei Wen*. Chitosan-based hydrogel incorporated with polydopamine and protoporphyrin for photothermal-oxidation sterilization of bacteria-infected wound therapy. Journal of Colloid and Interface Science, 2025, 678, 89.
第一作者7篇：
[1] Mei Wen, Pu Qiu, Jialan Meng, Wenjing Zhao, Xiao Wang, Shining Niu, Cheng Tao, Nuo Yu*, Zhigang Chen*, Dong Xie*. Multifunctional nanozymes for sonodynamic-enhanced immune checkpoint blockade therapy by inactivating PI3K/AKT signal pathway,Biomaterials,2025.
[2] Mei Wen, Nuo Yu, Zhigao Yi, Pu Qiu, Cheng Tao, Daniel K. Macharia, Meifang Zhu, Zhigang Chen*, and Xiaogang Liu*. On-demand phototoxicity inhibition of sensitizers and H2S-triggered in-situ activation for precise therapy of colon cancer. Nano Today,2023, 50, 101863.
[3]Mei Wen, Nuo Yu, Shiwen Wu, Mengmeng Huang, Pu Qiu, Qian Ren, Meifang Zhu, Zhigang Chen*. On-demand assembly of polymeric nanoparticles for longer-blood-circulation and disassembly in tumor for boosting sonodynamic therapy, Bioactive Materials, 2022, 18, 242.
[4] Mei Wen, Yaoyu Zhao, Pu Qiu, Qian Ren, Cheng Tao, Zhigang Chen, Nuo Yu. Efficient sonodynamic ablation of deep-seated tumors via cancer-cell-membrane camouflaged biocompatible nanosonosensitizers, Journal of Colloid and Interface Science, 2023,644, 388.
[5]Mei Wen, Xiaohan Liu, Nuo Yu, Pu Qiu, Daniel K. Macharia, Maoquan Li, Haijun Zhang, Zhigang Chen, Weishuai Lian.Multifunctional hemoporfin-Cu9S8-MnO2 for magnetic resonance imaging-guided catalytically-assisted photothermal-sonodynamic therapies, Journal of Colloid and Interface Science, 2022, 626, 77.
[6]Mei Wen, Jiayue Shen, Zhaojie Wang, Honghua Guo, Peng Geng, Nuo Yu, Maoquan Li, Haijun Zhang, Meifang Zhua, Zhigang Chen. A cascaded enzyme-loaded Fe–hemoporfin framework for synergistic sonodynamic-starvation therapy of tumors. Nanoscale, 2021, 13, 5910.
[7] Mei Wen, Shun Wang, Ruiqi Jiang, Yue Wang, Zhaojie Wang, Wanjian Yu, Peng Geng, Jindong Xia, Maoquan Li, Zhigang Chen. Tuning the NIR photoabsorption of CuWO4−x nanodots with oxygen vacancies for CT imaging guided photothermal therapy of tumors. Biomaterials Science2019, 7, 4651.
共同第一作者2篇：
[1] Yaoyu Zhao#,Mei Wen#, Nuo Yu,Cheng Tao, Qian Ren, Pu Qiu, Yue Zhang, Yue Wang, Jindong Xia, Zhigang Chen.Design and synthesis of cancer-cell-membrane-camouflaged hemoporfin-Cu9S8 nanoagents for homotypic tumor-targeted photothermal-sonodynamic therapy, Journal of Colloid and Interface Science, 2023,637, 225.
[2] Shuang Liu#, Mei Wen#, Mengmeng Huang, Haifeng Wang, Zhigang Chen, Nuo Yu. Nanoscale hematoporphrin-based frameworks for photo-sono synergistic cancer therapy via utilizing Al(III) as metal nodes rather than heavy metals, Journal of Colloid and Interface Science, 2022, 616, 23.
专利
[1] 陈志钢，文玫，文泽昱隆，马丹尼; 一种含Bi掺杂TiO2的光响应纳米材料、可逆变色油墨、可逆变色纤维及制备方法; 申请号：202410024384.4；申请日：2024年01月8日;
[2] 陈志钢, 文玫, 张晓婧,余诺,邱璞；一种具有单向排水、光热蒸发和杀菌功能的Janus 纤维敷料及其制备方法和应用；申请号：2024101052204；申请日：2024 年01月25日
